What Are Systemic Enzymes: And How Do They Work?

What Are Systemic Enzymes: And How Do They Work?

Systemic enzymes have gained significant attention in the world of health and wellness. But what exactly are they, and how do they work? This article will delve into the fascinating world of systemic enzymes, exploring their role in promoting overall health and well-being. Whether you're a health enthusiast or simply curious about natural remedies, this comprehensive guide will give you the knowledge you need to understand and harness the power of systemic enzymes.

What Are Systemic Enzymes?

Systemic enzymes are a type of enzyme that plays a crucial role in supporting various bodily functions. Unlike digestive enzymes that primarily aid in the breakdown of food, systemic enzymes work throughout the entire body, targeting inflammation, promoting healthy circulation, and supporting immune function. The body naturally produces these enzymes, but their levels may decline with age or due to certain health conditions. As a result, many individuals turn to systemic enzyme supplements to replenish these essential enzymes and support overall health and well-being.

How Does Systemic Enzymes Work?

Protein Breakdown

Systemic enzymes can break down proteins into smaller components. This process is essential for various physiological functions, including tissue repair, immune response, and metabolic processes. By breaking down proteins, systemic enzymes help optimize bodily functions and promote overall health.

Inflammation Reduction

Systemic enzymes possess anti-inflammatory properties and can help regulate the body's inflammatory response. They target pro-inflammatory molecules, such as cytokines, and break them down, reducing inflammation in the body. This can lead to a reduction in pain, improved joint health, and support faster recovery from injuries.

Immune System Support

Systemic enzymes play a crucial role in supporting immune function. They can break down immune complexes and assist in the clearance of pathogens, contributing to a stronger immune system. By enhancing immune function, systemic enzymes help support the body defend against infections and maintain overall health.

Can Systemic Enzymes Be Taken On an Empty Stomach?

Yes, systemic enzymes can be taken on an empty stomach. Taking them without food may enhance their effectiveness. When taken on an empty stomach, systemic enzymes are not utilized for digestion and can be absorbed more readily into the bloodstream. This allows them to circulate throughout the body and exert their beneficial effects on various physiological processes, such as reducing inflammation and supporting immune function. However, it is always recommended to follow the specific instructions provided by the manufacturer or consult with a healthcare professional for the optimal timing and dosage of systemic enzyme supplementation.

Are Proteolytic Enzymes The Same As Systemic Enzymes?

Yes, proteolytic enzymes and systemic enzymes are often used interchangeably to refer to the same type of enzymes. Proteolytic enzymes are a subset of systemic enzymes that specifically target and break down proteins. These enzymes play a crucial role in various physiological processes, including tissue repair, immune response, and metabolic functions. By breaking down proteins, proteolytic or systemic enzymes help optimize bodily functions, reduce inflammation, and support overall health. So, when referring to proteolytic enzymes or systemic enzymes, they are essentially referring to the same group of enzymes with similar functions and benefits.

How Do You Get Systemic Enzymes Naturally?

There are several ways to naturally obtain systemic enzymes:

  1. Through Diet: Certain foods contain natural systemic enzymes. Pineapple, for example, contains bromelain, a proteolytic enzyme with anti-inflammatory properties. Papaya also contains papain, another proteolytic enzyme known for its digestive benefits. Including these fruits in your diet can provide a natural source of systemic enzymes.
  2. Fermented Foods: Fermented foods like sauerkraut, kimchi, and miso contain enzymes produced during the fermentation process. These enzymes can have systemic benefits when consumed, aiding in digestion and supporting overall health.
  3. Raw Foods: Raw fruits and vegetables, especially when consumed in their natural, uncooked state, can contain enzymes that support systemic health. Heating and cooking can denature or destroy these enzymes, so incorporating raw foods into your diet can help ensure you're getting natural systemic enzymes.
  4. Dietary Supplement: If obtaining systemic enzymes through diet is challenging, or if you require higher levels of enzymes for specific health concerns, systemic supplements are available. These supplements are typically derived from natural sources and can provide a concentrated and convenient way to obtain systemic enzymes.

It's important to note that while natural sources of systemic enzymes can be beneficial, their concentration and effectiveness may vary. If you have specific health concerns or require higher levels of systemic enzymes, consulting with a healthcare professional can help determine the best approach for obtaining them naturally.

How Do You Get Systemic Enzymes Naturally?

What Is The Difference Between Systemic and Digestive Enzymes?

The main difference between systemic and digestive enzymes lies in their respective functions and locations within the body. Digestive enzymes, as the name suggests, are primarily involved in the process of digestion. These enzymes are produced in various parts of the digestive system, such as the salivary glands, stomach, pancreas, and small intestine. Their main role is to break down food into smaller molecules that can be absorbed and utilized by the body for energy and other functions. Digestive enzymes target specific macronutrients like carbohydrates, proteins, and fats, aiding in their digestion and absorption.

On the other hand, systemic enzymes work throughout the entire body, beyond the digestive system. These enzymes are involved in various physiological processes, such as immune response, tissue repair, and inflammation regulation. Systemic enzymes are produced in different organs and tissues, including the liver, pancreas, and white blood cells. Unlike digestive enzymes, systemic enzymes are not primarily involved in breaking down food. Instead, they target substances like proteins, fibrin, and immune complexes, playing a crucial role in promoting overall health and supporting bodily functions beyond digestion.

Is Boswellia Serrata The Same As Systemic Enzymes?

No, Boswellia serrata is not the same as systemic enzymes. Boswellia serrata, also known as Indian frankincense, is an herbal extract derived from the Boswellia tree. It is known for its anti-inflammatory properties and has been traditionally used in Ayurvedic medicine for various health conditions. Systemic enzymes refer to a group of enzymes that work throughout the body, targeting inflammation, promoting healthy circulation, and supporting immune function. While Boswellia serrata may have anti-inflammatory effects, it is not classified as a systemic enzyme. Systemic enzymes are typically derived from natural sources like plants, animals, or microorganisms and have a broader range of functions beyond just reducing inflammation.

How Does Serrazimes Compare To Systemic Enzymes?

Serrazimes is a specific blend of enzymes that includes both serrapeptase and protease enzymes. It is often used as a dietary supplement to support various aspects of health, including digestion and immune function. While serrazimes can have systemic effects, it is important to note that it is not synonymous with systemic enzymes as a whole. Systemic enzymes refer to a broader category of enzymes that work throughout the body, targeting inflammation, promoting circulation, and supporting immune function. While serrazimes may have some similar benefits, systemic enzymes encompass a wider range of enzymes with diverse functions beyond just digestion and immune support.

What Is Systemic Enzyme Therapy?

Systemic enzyme therapy, also known as systemic enzyme supplementation, is a therapeutic approach that involves the use of specific enzymes to support various physiological processes and promote overall health. It typically involves the oral consumption of enzyme supplements that contain a combination of proteolytic enzymes, such as bromelain, papain, and serrapeptase. These enzymes are designed to work throughout the body, targeting inflammation, promoting healthy circulation, and supporting immune function. Systemic enzyme therapy aims to optimize bodily functions, reduce inflammation, alleviate pain, support tissue repair, and enhance overall well-being. It is often used as a natural and complementary approach to support health and may be recommended for various conditions, including joint health, cardiovascular health, and immune system support.

Who Can Benefit From Systemic Enzymes?

  • Individuals experiencing chronic inflammation or inflammatory conditions
  • People with joint pain or arthritis
  • Those seeking natural support for cardiovascular health
  • Individuals with digestive issues or impaired digestion
  • People recovering from injuries or surgeries
  • Those looking to support immune function and overall wellness
  • Individuals with respiratory conditions or sinus issues
  • People with skin conditions or wound healing concerns
  • Those seeking natural support for detoxification processes
  • Individuals with autoimmune conditions or compromised immune systems


In conclusion, systemic enzymes play a vital role in promoting overall health and well-being. These powerful enzymes work throughout the body, targeting inflammation, supporting immune function, and optimizing various physiological processes. Whether obtained through natural sources like certain foods or taken as supplements, systemic enzymes offer a natural and complementary approach to improving health. From reducing pain and inflammation to supporting joint health, digestion, and immune function, systemic enzymes have the potential to benefit a wide range of individuals. By incorporating systemic enzymes into our routines, we can harness their potential and take proactive steps towards achieving optimal health and wellness.

Final Thoughts

Discover the power of Vitalzym Extra Strength, the definitive systemic enzyme supplement brought to you by World Nutrition. This vegetarian formula is intricately designed to maximize your body’s potential by boosting enzyme levels, enhancing immune function, reducing recovery time, and improving circulation. Infused with powerhouse ingredients like serrapeptase, bromelain, and papain, Vitalzym is your ticket to a thriving and healthful existence. Embrace the full spectrum of benefits that World Nutrition products offer and start your transformation today.*


  1. https://www.youtube.com/watch?v=s_PUPaszHAc
  2. https://www.healthline.com/nutrition/anti-inflammatory-diet-101
  3. https://www.emersonecologics.com/blog/post/a-closer-look-at-proteolytic-enzymes-and-your-immune-system
  4. https://www.eatingwell.com/article/8041356/foods-high-in-digestive-enzymes/
  5. https://en.wikipedia.org/wiki/Boswellia_serrata
  6. https://www.xtend-life.com/blogs/supplement-ingredients/serrapeptidase

These statements have not been evaluated by the food and drug administration (FDA). These products are not intended to diagnose, treat, cure, or prevent any disease.

In a recent Federal District Court case involving World Nutrition and AST Enzymes, the Judge found that the serrapeptase in AST products Serracor NK, Excellacor, Serrapeptase and Ultimate Metabolic Formula were only able to retain 27% of its enzyme activity after exposure to the stomach acid and that 73% of the serrapeptase will be degraded by the time it reaches the intestines.

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